7-Bromopyrido[2,3-b]pyrazine - Names and Identifiers
7-Bromopyrido[2,3-b]pyrazine - Physico-chemical Properties
Molecular Formula | C7H4BrN3
|
Molar Mass | 210.03 |
Density | 1.758±0.06 g/cm3(Predicted) |
Melting Point | 161-166°C |
Boling Point | 293.9±35.0 °C(Predicted) |
Flash Point | 131.5°C |
Vapor Presure | 0.00295mmHg at 25°C |
pKa | -1.00±0.30(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.698 |
MDL | MFCD01105748 |
7-Bromopyrido[2,3-b]pyrazine - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
WGK Germany | 3 |
7-Bromopyrido[2,3-b]pyrazine - Introduction
7-Bromopyrido[2,3-b]pyrazine is an organic compound with the chemical formula C≡H∞BrN₂. It is a white to light yellow solid, insoluble in water at room temperature, but soluble in organic solvents.
The compound is often used as an intermediate in organic synthesis and can be used to synthesize various functional compounds. Among them, it has a wide range of applications in the field of drug research. For example, it can be used as a synthetic starting material for anticancer drugs, anti-inflammatory drugs and the like.
7-Bromopyrido[2,3-b]pyrazine is prepared by various methods. One common method is by reacting benzo [3,4-b] thiophene with 3-bromopyridine. The specific steps are as follows: firstly, benzo [3,4-b] thiophene is reacted with alkaline hydroxide to generate a corresponding anionic compound; then, the anionic compound is reacted with 3-bromopyridine to generate a cyclization reaction to generate 7-Bromopyrido[2,3-b]pyrazine.
Regarding safety information, 7-Bromopyrido[2,3-b]pyrazine is a chemical and should be used in accordance with laboratory safety procedures. It may be irritating and damaging to the skin, eyes and respiratory system. During use, direct contact with skin and eyes should be avoided, and good ventilation conditions should be maintained. In case of misuse or contact, seek medical attention immediately.
Last Update:2024-04-09 21:01:54